Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 14/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24042589 | 1.00 | ALDH1A1 (0.55) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL24042532 | 1.00 | ALDH1A1 (0.55) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL24042531 | 1.00 | ALDH1A1 (0.55) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL24042587 | 0.87 | ALDH1A1 (0.52) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL30943126 | 0.87 | ALDH1A1 (0.52) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL23320392 | 0.84 | ALDH1A1 (0.57) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL30943210 | 0.82 | HTT (0.53) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL24042551 | 0.76 | ALDH1A1 (0.60) | ALDH1A1RAB9AHTTNAMPTGSK3B | |
| SCHEMBL24042586 | 0.75 | ALDH1A1 (0.47) | ALDH1A1RAB9AHTTNAMPT | |
| SCHEMBL30943283 | 0.75 | ALDH1A1 (0.47) | ALDH1A1RAB9AHTTNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |