Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 15/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320548 | 1.00 | ROCK2 (0.52) | ROCK2ROCK1NAMPTPTGES | |
| SCHEMBL23320580 | 0.84 | NAMPT (0.59) | ROCK2ROCK1NAMPT | |
| SCHEMBL30943163 | 0.84 | NAMPT (0.59) | ROCK2ROCK1NAMPT | |
| SCHEMBL30943169 | 0.81 | NAMPT (0.51) | NAMPT | |
| SCHEMBL24042576 | 0.81 | NAMPT (0.51) | NAMPT | |
| SCHEMBL24042574 | 0.81 | NAMPT (0.54) | ROCK2ROCK1NAMPT | |
| SCHEMBL30943269 | 0.81 | NAMPT (0.54) | ROCK2ROCK1NAMPT | |
| SCHEMBL24042594 | 0.80 | NAMPT (0.51) | ROCK2ROCK1NAMPT | |
| SCHEMBL30943149 | 0.80 | NAMPT (0.51) | ROCK2ROCK1NAMPT | |
| SCHEMBL23320485 | 0.75 | CHEK1 (0.37) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |