Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | F2R | P25116 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320529 | 1.00 | CYP19A1 (0.74) | CYP19A1ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL2420496 | 0.85 | CYP19A1 (1.00) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17199187 | 0.85 | CYP19A1 (0.74) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11763677 | 0.82 | CYP19A1 (0.70) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30943226 | 0.81 | CYP19A1 (0.69) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL23320486 | 0.81 | CYP19A1 (0.69) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17199051 | 0.77 | CYP19A1 (0.75) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17199054 | 0.77 | CYP19A1 (0.75) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30943237 | 0.77 | CYP19A1 (0.62) | CYP19A1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL23320552 | 0.77 | CYP19A1 (0.62) | CYP19A1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |