Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | F2RL3 | Q96RI0 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943237 | 1.00 | CYP19A1 (0.62) | CYP19A1F2RL3LMNAHPGDCHRNB2 | |
| SCHEMBL23320442 | 0.81 | IGF1R (0.40) | CYP19A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL30943195 | 0.81 | IGF1R (0.40) | CYP19A1LMNACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2420496 | 0.78 | CYP19A1 (1.00) | CYP19A1F2RL3LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30943232 | 0.77 | CYP19A1 (0.74) | CYP19A1F2RL3LMNAHPGDMAPT | |
| SCHEMBL17199187 | 0.77 | CYP19A1 (0.74) | CYP19A1F2RL3LMNAMAPTSMN1; SMN2 | |
| SCHEMBL23320529 | 0.77 | CYP19A1 (0.74) | CYP19A1F2RL3LMNAHPGDMAPT | |
| SCHEMBL3460244 | 0.76 | CHRNB2 (0.68) | LMNAHPGDCHRNB2CHRNA4MAOB | |
| SCHEMBL30833154 | 0.76 | CHRNB2 (0.68) | LMNAHPGDCHRNB2CHRNA4MAOB | |
| SCHEMBL2123821 | 0.75 | CYP19A1 (0.67) | CYP19A1F2RL3LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |