Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.56 |
| ▸ | ACP1 | P24666 | 1/20 | 0.55 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28530232 | 0.93 | NPC1 (0.59) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL30444394 | 0.89 | DYRK1A (0.61) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL28527319 | 0.88 | CNR1 (0.64) | DYRK1ACNR1NPC1RAB9ACSNK1D | |
| SCHEMBL30944323 | 0.88 | CNR1 (0.64) | DYRK1ACNR1NPC1RAB9ACSNK1D | |
| SCHEMBL31236386 | 0.86 | DYRK1A (0.60) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL28518076 | 0.86 | DYRK1A (0.60) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL4920969 | 0.86 | NPC1 (0.75) | DYRK1ACNR1NPC1RAB9AHDAC6 | |
| SCHEMBL30944290 | 0.84 | DYRK1A (0.62) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL28520293 | 0.84 | DYRK1A (0.62) | DYRK1ACNR1NPC1RAB9AHDAC3 | |
| SCHEMBL30944325 | 0.84 | DYRK1A (0.65) | DYRK1ANPC1RAB9AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |