Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.67 |
| ▸ | CSNK1D | P48730 | 13/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | ACP1 | P24666 | 1/20 | 0.57 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28519830 | 1.00 | DYRK1A (0.67) | DYRK1ACSNK1DADORA1CYP2D6ACP1 | |
| SCHEMBL31236382 | 0.99 | DYRK1A (0.65) | DYRK1ACSNK1DADORA1CYP2D6ACP1 | |
| SCHEMBL28518062 | 0.99 | DYRK1A (0.65) | DYRK1ACSNK1DADORA1CYP2D6ACP1 | |
| SCHEMBL30944303 | 0.99 | DYRK1A (0.65) | DYRK1ACSNK1DADORA1CYP2D6ACP1 | |
| SCHEMBL28527314 | 0.99 | DYRK1A (0.65) | DYRK1ACSNK1DADORA1CYP2D6ACP1 | |
| SCHEMBL30944285 | 0.84 | DYRK1A (0.60) | DYRK1ACSNK1DCYP2D6ACP1LRRK2 | |
| SCHEMBL28530536 | 0.84 | DYRK1A (0.60) | DYRK1ACSNK1DCYP2D6ACP1LRRK2 | |
| SCHEMBL30944343 | 0.84 | DYRK1A (0.69) | DYRK1ACSNK1DADORA1ACP1ADORA2A | |
| SCHEMBL28521697 | 0.84 | DYRK1A (0.69) | DYRK1ACSNK1DADORA1ACP1ADORA2A | |
| SCHEMBL30944395 | 0.83 | DYRK1A (0.67) | DYRK1ACSNK1DADORA1ACP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772080-A | Antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-112423746-B | Novel antimycobacterial heterocyclic amides | 克莱斯通公司 | 2024-06-28 | — | — | CN | disclosed |