Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.31 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.31 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660650 | 0.89 | CA12 (0.36) | CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL30944657 | 0.87 | CA12 (0.35) | CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL15176448 | 0.71 | PDE4B (0.39) | L3MBTL1UBE2N | |
| Trifluoroacetic Acid SCHEMBL5263179 | 0.68 | CES1 (0.39) | L3MBTL1CES1MEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL16342428 | 0.68 | HCAR2 (0.38) | L3MBTL1CES1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17064985 | 0.67 | GRN (0.33) | ALDH1A1SMN1; SMN2HPGDMAPTKDM4E | |
| Trifluoroacetic Acid SCHEMBL22397327 | 0.66 | L3MBTL1 (0.45) | L3MBTL1CES1MEN1ALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4345243 | 0.64 | CES1 (0.48) | L3MBTL1CES1ALDH1A1CYP1A2CA2 | |
| Trifluoroacetic Acid SCHEMBL30557285 | 0.64 | CES1 (0.39) | CES1KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL20571865 | 0.64 | L3MBTL1 (0.37) | L3MBTL1CES1ALDH1A1UBE2NPLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608821-A1 | PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS | Duke Street Bio Limited (GB) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024115465-A1 | PHARMACEUTICAL COMPOUNDS AS PARP7 AND/OR PARP1 INHIBITORS | Duke Street Bio Limited (GB) | 2024-06-06 | — | — | WO | disclosed |