Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1062994 | 1.00 | F10 (0.55) | F10TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2829176 | 0.88 | POLB (0.56) | F10CYP1A2CYP2D6CYP2C19MEN1 | |
| SCHEMBL12772560 | 0.87 | NPC1 (0.57) | F10TSHRMEN1KMT2ANAMPT | |
| SCHEMBL3662421 | 0.87 | F10 (0.53) | F10MEN1KMT2ANAMPTMAPT | |
| SCHEMBL13949629 | 0.87 | MEN1 (0.54) | F10MEN1KMT2ANAMPTMAPT | |
| SCHEMBL1066788 | 0.87 | F10 (0.53) | F10MEN1KMT2ANAMPTMAPT | |
| SCHEMBL8658147 | 0.86 | F10 (0.71) | F10TSHRCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1496857 | 0.86 | LCK (0.47) | TSHRCYP1A2CYP2D6CYP2C19ELANE | |
| SCHEMBL2732298 | 0.86 | HDAC1 (0.53) | F10ELANEPRTN3MEN1KMT2A | |
| SCHEMBL1705479 | 0.86 | GAA (0.53) | F10CYP1A2CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260014174-A1 | DUAL INHIBITORS FOR HDAC3 AND HIV-1 PR | PURDUE RESEARCH FOUNDATION (US) | 2026-01-15 | — | — | US | disclosed |
| EP-4629984-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BioVentures, LLC (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024123929-A1 | DEVELOPMENT OF POTENT DUAL HDAC/BRD4 INHIBITORS | BIOVENTURES, LLC (US) | 2024-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260014174-A1 | DUAL INHIBITORS FOR HDAC3 AND HIV-1 PR | HDAC3, HDAC1, HDAC11 | F10 3936/4885TSHR 1378/4885CYP1A2 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.