SCHEMBL30945337

SCHEMBL30945337

O=Cc1ccc(/C=C/c2ccc(N(CCCCO)CCCCO)cc2OCc2ccccc2)s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.44
HDAC8 Q9BY41 1/20 0.38
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CDK4 P11802 1/20 0.37
CCNB1 P14635 1/20 0.37
CCND1 P24385 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
PTGER1 P34995 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER3 P43115 1/20 0.37
PTGER2 P43116 1/20 0.37
ALDH1A1 P00352 1/20 0.34
KEAP1 Q14145 5/20 0.34
NFE2L2 Q16236 5/20 0.34
PLK1 P53350 2/20 0.34
ERN1 O75460 2/20 0.32
SLC16A3 O15427 1/20 0.32
SLC16A1 P53985 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20954438 1.00 BACE1 (0.44) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL21176726 1.00 BACE1 (0.44) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL10010288 0.95 BACE1 (0.45) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL11934282 0.95 BACE1 (0.45) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL21191543 0.93 BACE1 (0.46) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL11934281 0.90 BACE1 (0.45) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL10010555 0.89 BACE1 (0.46) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL11934172 0.89 BACE1 (0.46) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL21229892 0.89 BACE1 (0.44) BACE1HDAC8CCNB2CDK1CDK4
SCHEMBL20954632 0.86 BACE1 (0.46) BACE1HDAC8CCNB2CDK1CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109415468-B Electro-optical polymers 国立研究开发法人情报通信研究机构 2024-06-07 CN disclosed