SCHEMBL11934282

SCHEMBL11934282

CCCCN(CCCCO)c1ccc(/C=C/c2ccc(C=O)s2)c(OCc2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.45
SLC16A3 O15427 2/20 0.38
SLC16A1 P53985 2/20 0.38
HDAC8 Q9BY41 1/20 0.38
APP P05067 2/20 0.35
ATG4B Q9Y4P1 1/20 0.35
CCNB2 O95067 1/20 0.34
CDK1 P06493 1/20 0.34
CDK4 P11802 1/20 0.34
CCNB1 P14635 1/20 0.34
CCND1 P24385 1/20 0.34
CCNB3 Q8WWL7 1/20 0.34
PTGER1 P34995 1/20 0.34
PTGER4 P35408 1/20 0.34
PTGER3 P43115 1/20 0.34
PTGER2 P43116 1/20 0.34
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10010288 1.00 BACE1 (0.45) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL20954438 0.95 BACE1 (0.44) BACE1SLC16A3SLC16A1HDAC8CCNB2
SCHEMBL21176726 0.95 BACE1 (0.44) BACE1SLC16A3SLC16A1HDAC8CCNB2
SCHEMBL30945337 0.95 BACE1 (0.44) BACE1SLC16A3SLC16A1HDAC8CCNB2
SCHEMBL11934281 0.95 BACE1 (0.45) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL10010555 0.95 BACE1 (0.46) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL11934172 0.95 BACE1 (0.46) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL21229892 0.92 BACE1 (0.44) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL12837173 0.90 BACE1 (0.43) BACE1SLC16A3SLC16A1HDAC8APP
SCHEMBL21191543 0.89 BACE1 (0.46) BACE1HDAC8CCNB2CDK1CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480224-B1 ELECTRO-OPTIC POLYMER NAT INST INF & COMM TECH (JP) 2024-06-12 EP disclosed
CN-109415468-B Electro-optical polymers 国立研究开发法人情报通信研究机构 2024-06-07 CN disclosed
EP-3748420-B1 ELECTRO-OPTICAL POLYMER NAT INST INF & COMM TECH (JP) 2024-01-17 EP disclosed
EP-3748420-B1 ELECTRO-OPTICAL POLYMER NAT INST INF & COMM TECH (JP) 2024-01-17 EP disclosed
US-11236188-B2 Electro-optic polymer NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2022-02-01 US disclosed
US-11236188-B2 Electro-optic polymer NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2022-02-01 US disclosed
US-20210032228-A1 ELECTRO-OPTIC POLYMER NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2021-02-04 US disclosed
EP-3748420-A1 ELECTRO-OPTICAL POLYMER National Institute of Information and Communications Technology (JP) 2020-12-09 EP disclosed
EP-3748420-A1 ELECTRO-OPTICAL POLYMER National Institute of Information and Communications Technology (JP) 2020-12-09 EP disclosed
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2020-08-25 US disclosed
US-9488755-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2016-11-08 US disclosed
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2016-11-03 US disclosed
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2016-11-03 US disclosed
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2015-02-19 US disclosed
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME NAT INST INF & COMM TECH (JP) 2015-02-19 US disclosed
US-8846955-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2014-09-30 US disclosed
US-8846955-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY (JP) 2014-09-30 US disclosed
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 2012-07-05 US disclosed
WO-2011024774-A1 SECOND-ORDER NON-LINEAR OPTICAL COMPOUND AND NON-LINEAR OPTICAL ELEMENT COMPRISING SAME 独立行政法人情報通信研究機構 (JP) 2011-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318889-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-11236188-B2 Electro-optic polymer UACA, ELAVL1, EYA3 BACE1 4855/4885SLC16A3 84/4885SLC16A1 187/4885
US-20150048284-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-10754064-B2 Second-order nonlinear optical compound and nonlinear optical element comprising the same OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885
US-20210032228-A1 ELECTRO-OPTIC POLYMER TECR, AQP3, LAGE3 BACE1 4297/4885SLC16A3 263/4885SLC16A1 1283/4885
US-20120172599-A1 SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME OGFOD1, OCIAD2, OCIAD1 BACE1 4124/4885SLC16A3 3538/4885SLC16A1 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.