Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 11/20 | 0.57 |
| ▸ | CSF1R | P07333 | 9/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30883978 | 0.87 | DYRK2 (0.57) | DYRK2CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL26448024 | 0.87 | DYRK2 (0.57) | DYRK2CSF1RPDGFRBKITPDGFRA | |
| SCHEMBL28523402 | 0.79 | DYRK2 (0.66) | DYRK2 | |
| SCHEMBL29212669 | 0.78 | DYRK2 (0.72) | DYRK2 | |
| SCHEMBL29754442 | 0.76 | SMN1; SMN2 (0.50) | DYRK2 | |
| SCHEMBL16666086 | 0.75 | MAPT (0.59) | CSF1R | |
| SCHEMBL18453934 | 0.74 | CDK4 (0.55) | — | |
| SCHEMBL26447936 | 0.74 | DYRK2 (0.98) | DYRK2 | |
| Hydrochloric Acid SCHEMBL30569704 | 0.74 | DYRK2 (1.00) | DYRK2 | |
| Hydrochloric Acid SCHEMBL26679974 | 0.74 | DYRK2 (1.00) | DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119866-A1 | BENZOTHIAZOLE PYRIMIDINEAMINE DYRK2 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2024-06-13 | — | — | WO | disclosed |