Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 5/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084273 | 0.89 | CNR2 (0.54) | CNR2CNR1PPARA | |
| SCHEMBL3096389 | 0.84 | KDM4E (0.52) | CNR2CNR1PPARA | |
| SCHEMBL923743 | 0.82 | CNR2 (0.62) | CNR2CNR1RPA1PPARA | |
| SCHEMBL3096108 | 0.82 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL3103578 | 0.82 | CNR1 (0.62) | CNR2CNR1 | |
| SCHEMBL3098054 | 0.81 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL3096122 | 0.81 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL3098223 | 0.81 | CNR1 (0.44) | CNR2CNR1 | |
| SCHEMBL3099903 | 0.81 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL3093507 | 0.81 | CNR1 (0.46) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803799-B2 | such as 1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-5-(selenophen-2-yl)-1H-pyrazole-3-carboxamide, used for treating cannabinoid-receptor mediated disorders selected from obesity, metabolic syndrome, drug abuse and dependence or neuropathic pain | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2010-09-28 | — | — | US | disclosed |
| EP-2084135-A2 | PYRAZOLE COMPOUNDS | National Health Research Institutes (TW) | 2009-08-05 | — | — | EP | disclosed |
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-02-12 | — | — | US | disclosed |
| WO-2008060771-A2 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-05-22 | — | — | WO | disclosed |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-17 | — | — | US | disclosed |
| US-20080021031-A1 | SELENOPHENE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTE (TW) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042864-A2 | PYRAZOLE COMPOUNDS | CNR2, CNR1, GPR18 | CNR2 1/4885LMNA 4767/4885CNR1 2/4885 |
| US-20080021031-A1 | SELENOPHENE COMPOUNDS | CNR2, CNR1, SELENOI | CNR2 1/4885LMNA 4847/4885CNR1 2/4885 |
| US-20080090809-A1 | PYRAZOLE COMPOUNDS | CNR2, CNR1, GPR18 | CNR2 1/4885LMNA 4767/4885CNR1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.