Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23293802 | 1.00 | MAPT (0.46) | MAPTHDAC3HDAC1HDAC2AAK1 | |
| SCHEMBL22393793 | 0.88 | AAK1 (0.49) | AAK1KMT2APOLBIRAK4 | |
| SCHEMBL8339616 | 0.85 | AAK1 (0.53) | HDAC3HDAC1HDAC2AAK1KMT2A | |
| SCHEMBL25151822 | 0.84 | HTT (0.52) | MAPTHDAC3HDAC1HDAC2AAK1 | |
| SCHEMBL23316233 | 0.83 | PTPN2 (0.56) | KMT2APOLB | |
| SCHEMBL22600529 | 0.81 | ROCK2 (0.47) | MAPTHDAC3HDAC1HDAC2PARP1 | |
| SCHEMBL22701155 | 0.81 | PTPN2 (0.50) | MAPTHDAC1HDAC2PARP1KMT2A | |
| SCHEMBL18018576 | 0.78 | AAK1 (0.44) | MAPTAAK1KMT2APOLBIRAK4 | |
| SCHEMBL18170428 | 0.76 | PIK3C3 (0.56) | GSK3B | |
| SCHEMBL29676896 | 0.76 | PIK3C3 (0.56) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112469707-B | Preventive or therapeutic agent for spinal muscular atrophy | 利伯纳生物科学株式会社 | 2024-06-21 | — | — | CN | disclosed |