Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 8/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200817 | 0.91 | EPHX1 (0.68) | EPHX1ALDH1A1CA12CA1CA2 | |
| SCHEMBL13712552 | 0.88 | EPHX1 (0.55) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL1457410 | 0.88 | EPHX1 (0.55) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL24817359 | 0.88 | EPHX1 (0.55) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL6865392 | 0.88 | EPHX1 (0.55) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL4011556 | 0.86 | EPHX1 (0.58) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL4011553 | 0.86 | EPHX1 (0.58) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL6874691 | 0.86 | EPHX1 (0.58) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL1896900 | 0.86 | EPHX1 (0.58) | EPHX1ALDH1A1HSD11B1CYP2C9USP30 | |
| SCHEMBL470552 | 0.86 | HSD11B1 (0.68) | EPHX1HSD11B1CYP2C9USP30CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598535-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | New York University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076610-A2 | INHIBITORS OF SPNS2 AND USES THEREOF | NEW YORK UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |