SCHEMBL30948980

SCHEMBL30948980

Cc1nc(Cl)ccc1-c1cn(C)c(OC(F)F)n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30948987 0.83 PDCD1LG2 (0.34)
SCHEMBL30948973 0.76 METAP2 (0.32) METAP2
SCHEMBL30948982 0.74 PTGS1 (0.33) METAP2
SCHEMBL25435574 0.72 METAP2 (0.35) METAP2
SCHEMBL31687272 0.69 AXL (0.30)
SCHEMBL25435848 0.66 LRRK2 (0.41) METAP2
SCHEMBL25437157 0.65 IRAK4 (0.36) METAP2
SCHEMBL3512272 0.63 MAPT (0.41)
SCHEMBL6674197 0.62 PDE4B (0.30)
SCHEMBL19305211 0.62 KDM4E (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4620955-A1 MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF Changchun Genescience Pharmaceutical Co., Ltd. (CN) 2025-09-24 EP disclosed
CN-120202199-A MC4R antagonist compound, pharmaceutical composition and application thereof in medicine 长春金赛药业有限责任公司 2025-06-24 CN disclosed
WO-2024104452-A1 MC4R ANTAGONIST COMPOUND, PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL USE THEREOF 长春金赛药业有限责任公司 2024-05-23 WO disclosed