Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SCN2B | O60939 | 1/20 | 0.41 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25078533 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL1504503 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL30949218 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL1504529 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL1504547 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1MAPTRAB9A | |
| SCHEMBL16474405 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KDM4EKMT2ASMN1; SMN2MAPT | |
| SCHEMBL25077892 | 0.82 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL30159505 | 0.82 | PTGS1 (0.44) | KDM4EKMT2ASMN1; SMN2GAASCN2B | |
| SCHEMBL16672403 | 0.82 | PTGS1 (0.44) | KDM4EKMT2ASMN1; SMN2GAASCN2B | |
| SCHEMBL30202817 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4667458-A1 | PHARMACEUTICAL COMPOSITION FOR TREATMENT OF CANCER, COMPRISING SOS1 INHIBITOR AND ANTICANCER DRUG | Kanaph Therapeutics Inc. (KR) | 2025-12-24 | — | — | EP | disclosed |
| CN-118119600-A | SOS1 inhibitors and uses thereof | 治纳辅医药科技有限公司 | 2024-05-31 | — | — | CN | disclosed |