Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15634008 | 0.73 | HTT (0.50) | HTTALDH1A1L3MBTL1MEN1MAPT | |
| SCHEMBL4712339 | 0.71 | HTT (0.76) | HTTMAPTPOLBSMN1; SMN2LMNA | |
| SCHEMBL14874665 | 0.70 | HTT (0.50) | HTTALDH1A1MEN1KMT2ACYP11B1 | |
| SCHEMBL27585502 | 0.70 | NPSR1 (0.44) | LTA4HALDH1A1CYP11B1CYP11B2POLB | |
| SCHEMBL1425001 | 0.70 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2CYP2D6ATM | |
| SCHEMBL25986524 | 0.70 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2CYP2D6ATM | |
| SCHEMBL27884 | 0.70 | LTA4H (0.81) | LTA4HALDH1A1SMN1; SMN2CYP2D6ATM | |
| SCHEMBL23094537 | 0.70 | HTT (0.42) | HTTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL23094450 | 0.70 | MEN1 (0.39) | HTTALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL6620402 | 0.69 | NPC1 (0.43) | HTTALDH1A1L3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113637005-B | KRAS inhibitors for cancer treatment | 泰励生物科技（上海）有限公司 | 2024-05-24 | — | — | CN | disclosed |