Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29285003 | 1.00 | NLRP3 (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29573999 | 0.83 | GRIN2D (0.43) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21722642 | 0.83 | GRIN2D (0.43) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30951196 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21722656 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL23033128 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30951204 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29284864 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29575133 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29284837 | 0.81 | GRIN2D (0.41) | NLRP3GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251393-A | Novel substituted sulfonylurea compounds as inhibitors of interleukin-1 activity | 唯久生物技术(苏州)有限公司 | 2024-06-25 | — | — | CN | disclosed |