Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 15/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951997 | 0.86 | SCN9A (0.62) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951993 | 0.86 | SCN9A (0.62) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951988 | 0.86 | SCN9A (0.60) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30952008 | 0.86 | SCN9A (0.49) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951950 | 0.84 | SCN9A (0.76) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951949 | 0.84 | SCN9A (0.76) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951982 | 0.84 | SCN9A (0.52) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951998 | 0.83 | SCN9A (0.56) | SCN9AP2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL30951999 | 0.82 | SCN9A (0.54) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951989 | 0.82 | SCN9A (0.65) | SCN9AALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |