Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473332 | 1.00 | PRCP (0.54) | PRCPOPRM1OPRK1RETHTR2A | |
| SCHEMBL8024199 | 0.84 | PRCP (0.56) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL21890121 | 0.84 | PRCP (0.56) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL23057928 | 0.84 | PRCP (0.56) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL3245156 | 0.83 | KCNN2 (0.55) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL3255532 | 0.83 | PRCP (0.54) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL30818243 | 0.82 | HTR2A (0.44) | PRCPOPRM1OPRK1RETHTR2A | |
| Hydrochloric Acid SCHEMBL3263954 | 0.81 | KCNN2 (0.56) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL3248329 | 0.81 | PRCP (0.53) | PRCPOPRM1OPRK1OPRD1OPRL1 | |
| SCHEMBL19020713 | 0.81 | PRCP (0.53) | PRCPOPRM1OPRK1OPRD1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112789276-B | Analgesic compounds, process for their preparation and their use in medicine | 上海海雁医药科技有限公司 | 2024-07-30 | — | — | CN | disclosed |