Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.51 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.51 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3254136 | 0.98 | PRCP (0.53) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL3248329 | 0.98 | PRCP (0.53) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| Hydrochloric Acid SCHEMBL3253137 | 0.97 | PRCP (0.51) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL3245156 | 0.97 | KCNN2 (0.55) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| Hydrochloric Acid SCHEMBL3263954 | 0.95 | KCNN2 (0.56) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL14417432 | 0.92 | OPRM1 (0.48) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL8820261 | 0.92 | OPRM1 (0.50) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL8011451 | 0.88 | PRCP (0.53) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL19020713 | 0.88 | PRCP (0.53) | PRCPOPRM1OPRK1SLC6A4KCNN2 | |
| SCHEMBL23057928 | 0.84 | PRCP (0.56) | PRCPOPRM1OPRK1SLC6A4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998775-B1 | BIS1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES AND THEIR USES AS PHARMACEUTICALS | UNIV LIEGE (BE) | 2010-05-19 | — | — | EP | claimed |