Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30952859 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL24915610 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL15259719 | 0.86 | HRH4 (0.47) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL17768583 | 0.81 | HRH4 (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL20417166 | 0.79 | HRH4 (0.41) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL15314267 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL30952861 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL24915369 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL17258436 | 0.78 | HRH4 (0.44) | KDM4EALDH1A1HRH4GRIN2DGRIN3B | |
| SCHEMBL30080485 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1HRH4GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373808-A | Substituted pyrimidine or pyridine amine derivatives, compositions thereof and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-113748110-B | Substituted pyrimidine or pyridine amine derivatives, compositions thereof and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |