Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625923 | 1.00 | KDM4E (0.79) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30952930 | 1.00 | KDM4E (0.79) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30041634 | 0.96 | KDM4E (0.73) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL24961374 | 0.96 | KDM4E (0.73) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL24824319 | 0.94 | KDM4E (0.70) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL23625932 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30952894 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30952932 | 0.91 | KDM4E (0.65) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL666309 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL31082315 | 0.89 | KDM4E (1.00) | KDM4EALDH1A1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767090-B | Tricyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-05-28 | — | — | CN | disclosed |