⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361366 | 0.80 | — | — | |
| SCHEMBL15313188 | 0.77 | — | — | |
| SCHEMBL15313196 | 0.77 | — | — | |
| SCHEMBL6630234 | 0.70 | — | — | |
| SCHEMBL309666 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL704489 | 0.69 | — | — | |
| SCHEMBL706567 | 0.69 | — | — | |
| SCHEMBL4276960 | 0.67 | — | — | |
| SCHEMBL5251660 | 0.67 | — | — | |
| SCHEMBL704644 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093419-B2 | Method of producing organosilicon compound | JSR CORPORATION (JP) | 2012-01-10 | — | — | US | disclosed |
| JP-2010006795-A | METHOD FOR PRODUCING ORGANOSILICON COMPOUND | JSR CORP | 2010-01-14 | — | — | JP | disclosed |
| US-20090299086-A1 | METHOD OF PRODUCING ORGANOSILICON COMPOUND | JSR CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-1033367-A2 | Process for the preparation of optically active triazole derivatives and their imidazolidin-2-one intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5677464-A | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0687672-A2 | Production of optically active triazole compounds and their intermediates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0530994-A1 | Quinazoline derivatives as inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1993-03-10 | — | — | EP | disclosed |
| WO-1993004047-A1 | QUINAZOLINE DERIVATIVES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | MERCK & CO., INC. (US) | 1993-03-04 | — | — | WO | disclosed |