SCHEMBL30953089

SCHEMBL30953089

CC(C)n1nccc1C(=O)N[C@H](C(=O)Nc1cc(C(NC(=O)CC(F)(F)F)C2CC2)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.36
▸ ACACB O00763 1/20 0.35
▸ TBK1 Q9UHD2 2/20 0.34
▸ NR3C2 P08235 1/20 0.33
▸ WDR5 P61964 3/20 0.33
▸ NAMPT P43490 1/20 0.31
▸ PYGL P06737 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ PSMB11 A5LHX3 1/20 0.30
▸ PSMA7 O14818 1/20 0.30
▸ PSMB1 P20618 1/20 0.30
▸ PSMA1 P25786 1/20 0.30
▸ PSMA2 P25787 1/20 0.30
▸ PSMA3 P25788 1/20 0.30
▸ PSMA4 P25789 1/20 0.30
▸ PSMB8 P28062 1/20 0.30
▸ PSMB9 P28065 1/20 0.30
▸ PSMA5 P28066 1/20 0.30
▸ PSMB4 P28070 1/20 0.30
▸ PSMB6 P28072 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953055 0.94 IL17A (0.34) IL17ATBK1NR3C2WDR5NAMPT
SCHEMBL30953014 0.94 IL17A (0.34) IL17ATBK1NR3C2WDR5NAMPT
SCHEMBL30952934 0.86 NR3C2 (0.35) IL17AACACBTBK1NR3C2NAMPT
SCHEMBL30953480 0.86 IL17A (0.35) IL17AACACBTBK1NR3C2WDR5
SCHEMBL30952931 0.85 CTSS (0.37) IL17ATBK1
SCHEMBL30952964 0.85 CTSS (0.37) IL17ATBK1
SCHEMBL30953085 0.84 MEN1 (0.34) IL17A
SCHEMBL30953028 0.83 MAPK1 (0.33) IL17ATBK1NR3C2
SCHEMBL30953241 0.81 ACACB (0.36) ACACBTBK1NR3C2
SCHEMBL30953025 0.80 IL17A (0.47) IL17AACACBTBK1NR3C2WDR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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