SCHEMBL30953110

SCHEMBL30953110

COC[C@H](c1ccnc(NC(=O)[C@@H](NC(=O)c2nonc2C2CC2)C(C2CC2)C2CC2)c1)N1C[C@@H](C(F)(F)F)NC1=O

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 10/20 0.47
▸ ABCB11 O95342 1/20 0.37
▸ CHRM2 P08172 1/20 0.37
▸ SLCO1B1 Q9Y6L6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30952995 0.93 IL17A (0.49) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953492 0.90 IL17A (0.44) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952965 0.90 IL17A (0.44) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953066 0.88 IL17A (0.53) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952981 0.87 IL17A (0.48) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953147 0.87 IL17A (0.43) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953074 0.86 IL17A (0.42) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953000 0.84 IL17A (0.44) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953426 0.84 ABCB11 (0.40) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952967 0.82 IL17A (0.53) IL17A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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