SCHEMBL30953337

SCHEMBL30953337

Cn1nccc1C(=O)N[C@H](C(=O)Nc1cc(C[C@H]2C[C@@H](C(F)(F)F)NC2=O)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.33
▸ CDK2 P24941 2/20 0.33
▸ CCNE1 P24864 1/20 0.33
▸ GSK3B P49841 1/20 0.33
▸ F11 P03951 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ MGAT2 Q10469 1/20 0.32
▸ MBOAT4 Q96T53 1/20 0.31
▸ BUB1 O43683 1/20 0.31
▸ LMNA P02545 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953141 0.93 IL17A (0.34) IL17A
SCHEMBL30952959 0.92 IL17A (0.32) IL17ACDK2CCNE1GSK3BLMNA
SCHEMBL30953504 0.86 NAMPT (0.32) IL17A
SCHEMBL30953102 0.86 — —
SCHEMBL30953039 0.86 IL17A (0.38) IL17A
SCHEMBL30952938 0.85 IL17A (0.45) IL17ACDK2CCNE1GSK3BF11
SCHEMBL30953158 0.85 IL17A (0.37) IL17A
SCHEMBL30953152 0.85 IL17A (0.35) IL17A
SCHEMBL30953010 0.85 IL17A (0.35) IL17A
SCHEMBL30952925 0.85 IL17A (0.33) IL17A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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