SCHEMBL30952938

SCHEMBL30952938

Cn1nccc1C(=O)N[C@H](C(=O)Nc1cc(CN2C[C@@H](C(F)(F)F)NC2=O)ccn1)C1CCC(F)(F)CC1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ IL17A Q16552 6/20 0.45
▸ ABCB11 O95342 1/20 0.32
▸ CHRM2 P08172 1/20 0.32
▸ SLCO1B1 Q9Y6L6 1/20 0.32
▸ CTSS P25774 1/20 0.32
▸ MGAT2 Q10469 1/20 0.32
▸ CDK2 P24941 2/20 0.32
▸ CCNE1 P24864 1/20 0.32
▸ GSK3B P49841 1/20 0.32
▸ MBOAT4 Q96T53 1/20 0.31
▸ BUB1 O43683 1/20 0.31
▸ UCHL1 P09936 1/20 0.31
▸ USP30 Q70CQ3 1/20 0.31
▸ F11 P03951 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953013 0.92 IL17A (0.46) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952976 0.92 IL17A (0.36) IL17AMGAT2CDK2CCNE1GSK3B
SCHEMBL30952975 0.91 IL17A (0.43) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952940 0.86 IL17A (0.39) IL17ACDK2CCNE1GSK3BMBOAT4
SCHEMBL30953337 0.85 IL17A (0.33) IL17ACTSSMGAT2CDK2CCNE1
SCHEMBL30953075 0.85 IL17A (0.38) IL17AABCB11CHRM2SLCO1B1CTSS
SCHEMBL30953030 0.85 IL17A (0.47) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30952974 0.85 IL17A (0.42) IL17AABCB11CHRM2SLCO1B1
SCHEMBL30953104 0.85 IL17A (0.38) IL17A
SCHEMBL30953419 0.85 IL17A (0.34) IL17AABCB11CHRM2SLCO1B1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP claimed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO claimed
EP-4630115-A1 THERAPEUTIC COMPOUNDS Sanofi (FR) 2025-10-15 — — EP disclosed
WO-2024121427-A1 THERAPEUTIC COMPOUNDS SANOFI (FR) 2024-06-13 — — WO disclosed
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