Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070169 | 0.81 | ATR (0.44) | TGFBR1AAK1GSK3BDYRK1AATR | |
| SCHEMBL2808080 | 0.81 | ATR (0.44) | TGFBR1AAK1GSK3BDYRK1ANR3C2 | |
| SCHEMBL22945805 | 0.80 | ATR (0.43) | TGFBR1AAK1GSK3BDYRK1AATR | |
| SCHEMBL27962539 | 0.80 | ATR (0.43) | AAK1GSK3BDYRK1AATRIRAK4 | |
| SCHEMBL28741827 | 0.80 | ATR (0.43) | TGFBR1AAK1GSK3BDYRK1AATR | |
| SCHEMBL29626780 | 0.80 | ATR (0.43) | TGFBR1AAK1GSK3BDYRK1AATR | |
| SCHEMBL30953559 | 0.80 | AAK1 (0.42) | AAK1ATRCYP3A4IRAK4 | |
| SCHEMBL30953364 | 0.79 | GSK3B (0.38) | TGFBR1AAK1GSK3BDYRK1ANR3C2 | |
| SCHEMBL27955914 | 0.79 | ATR (0.42) | TGFBR1AAK1GSK3BDYRK1AATR | |
| SCHEMBL30953539 | 0.77 | IGF1R (0.36) | TGFBR1AAK1GSK3BDYRK1ANR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630115-A1 | THERAPEUTIC COMPOUNDS | Sanofi (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121427-A1 | THERAPEUTIC COMPOUNDS | SANOFI (FR) | 2024-06-13 | — | — | WO | disclosed |