Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30953247 | 0.90 | AAK1 (0.35) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL30953063 | 0.88 | AAK1 (0.42) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL30953125 | 0.86 | AAK1 (0.41) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL30953245 | 0.82 | NR3C2 (0.36) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL30953272 | 0.82 | AAK1 (0.39) | IGF1RAAK1CYP3A4ATR | |
| SCHEMBL30953361 | 0.81 | RAB9A (0.35) | NPC1RAB9AMEN1TP53TSHR | |
| SCHEMBL30953420 | 0.78 | SMYD3 (0.38) | NPC1RAB9AALOX12 | |
| SCHEMBL30953364 | 0.77 | GSK3B (0.38) | IGF1RTGFBR1AAK1GSK3BDYRK1A | |
| SCHEMBL30953376 | 0.77 | TGFBR1 (0.41) | IGF1RTGFBR1AAK1GSK3BDYRK1A | |
| SCHEMBL30952937 | 0.75 | TRPV1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630115-A1 | THERAPEUTIC COMPOUNDS | Sanofi (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121427-A1 | THERAPEUTIC COMPOUNDS | SANOFI (FR) | 2024-06-13 | — | — | WO | disclosed |