Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.37 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30953392 | 0.84 | CCNE1 (0.41) | IGF1RCCNE1CDK2GSK3BRIOK2 | |
| SCHEMBL30953287 | 0.83 | IGF1R (0.47) | IGF1RCCR2CYP17A1NR3C2L3MBTL1 | |
| SCHEMBL30468519 | 0.80 | GABRP (0.47) | IGF1RGSK3BRIOK2LOXL2CCR2 | |
| SCHEMBL2771914 | 0.80 | GABRP (0.47) | IGF1RGSK3BRIOK2LOXL2CCR2 | |
| SCHEMBL12277478 | 0.80 | IGF1R (0.46) | IGF1RGSK3BRIOK2MAPK10GSK3A | |
| SCHEMBL5779556 | 0.79 | NR3C2 (0.46) | IGF1RLOXL2CCR2CYP17A1NR3C2 | |
| SCHEMBL5780771 | 0.79 | NR3C2 (0.49) | IGF1RLOXL2CCR2CYP17A1NR3C2 | |
| SCHEMBL20536182 | 0.79 | IGF1R (0.46) | IGF1RGSK3BRIOK2MAPK10GSK3A | |
| SCHEMBL30468562 | 0.79 | IGF1R (0.46) | IGF1RGSK3BRIOK2MAPK10GSK3A | |
| SCHEMBL1940483 | 0.77 | IGF1R (0.48) | IGF1RGSK3BCCR2CYP17A1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630115-A1 | THERAPEUTIC COMPOUNDS | Sanofi (FR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121427-A1 | THERAPEUTIC COMPOUNDS | SANOFI (FR) | 2024-06-13 | — | — | WO | disclosed |