Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30953777 | 0.88 | KDM4E (0.50) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL3593417 | 0.88 | KDM4E (0.50) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL30953576 | 0.86 | KDM4E (0.54) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL30953816 | 0.85 | KDM4E (0.44) | KDM4EATMHTTALDH1A1LMNA | |
| SCHEMBL30953642 | 0.84 | KDM4E (0.55) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL11105631 | 0.84 | KDM4E (0.55) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL30953605 | 0.84 | KDM4E (0.55) | KDM4EATMHTTALDH1A1L3MBTL1 | |
| SCHEMBL1451122 | 0.79 | ALDH1A1 (0.61) | KDM4EHTTALDH1A1LMNACRHBP | |
| SCHEMBL30953811 | 0.79 | ALDH1A1 (0.61) | KDM4EHTTALDH1A1LMNACRHBP | |
| SCHEMBL3594528 | 0.78 | RAF1 (0.46) | KDM4EATMHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |