Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318941 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4ETRPV1LMNACRHBP | |
| SCHEMBL30953823 | 0.89 | KDM4E (0.45) | ALDH1A1KDM4ETRPV1HTTCNR1 | |
| SCHEMBL30953863 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4ETRPV1LMNACRHBP | |
| SCHEMBL2321310 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4ETRPV1LMNACRHBP | |
| SCHEMBL3592481 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNACRHBPHTT | |
| SCHEMBL30953673 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNACRHBPHTT | |
| SCHEMBL17027030 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4ETRPV1LMNACRHBP | |
| SCHEMBL1451122 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNACRHBPHTT | |
| SCHEMBL30953811 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KDM4ELMNACRHBPHTT | |
| SCHEMBL2319623 | 0.81 | MAOB (0.47) | ALDH1A1KDM4ESMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |