Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | MPI | P34949 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PARP11 | Q9NR21 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429558 | 1.00 | PARP10 (0.54) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL1451498 | 0.90 | PARP10 (0.48) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12894753 | 0.87 | PARP10 (0.58) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2259264 | 0.79 | KIF11 (0.54) | PARP10PARP1TDP2SMN1; SMN2KIF11 | |
| SCHEMBL29783110 | 0.79 | KIF11 (0.54) | PARP10PARP1TDP2SMN1; SMN2KIF11 | |
| SCHEMBL3534887 | 0.78 | PARP10 (0.51) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3105252 | 0.77 | MEN1 (0.54) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL30274589 | 0.77 | MEN1 (0.54) | PARP10PARP1MEN1KMT2AALDH1A1 | |
| SCHEMBL2632664 | 0.75 | KIF11 (0.54) | PARP10PARP1TDP2SMN1; SMN2KIF11 | |
| SCHEMBL1735429 | 0.75 | PARP10 (0.60) | PARP10PARP1PARP11TDP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |