Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427382 | 0.85 | NR2E3 (0.48) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL25563858 | 0.81 | HSD17B10 (0.45) | HSD17B10ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL31525855 | 0.81 | HSD17B10 (0.45) | HSD17B10ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL9427348 | 0.79 | HSD17B10 (0.42) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL9741027 | 0.78 | NPSR1 (0.44) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL9741899 | 0.75 | NPSR1 (0.43) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL9427276 | 0.75 | NR2E3 (0.43) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL9741908 | 0.75 | NR2E3 (0.46) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL9741511 | 0.75 | NR2E3 (0.41) | HSD17B10ALDH1A1HTTTDP1HPGD | |
| SCHEMBL31649899 | 0.75 | L3MBTL1 (0.54) | HSD17B10ALDH1A1HTTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024140431-A1 | COMPOUNDS COMPRISING HETEROARYL RINGS AND COMPOSITIONS AND METHODS THEREOF | IONGEN THERAPEUTICS CO., LTD. (CN) | 2024-07-04 | — | — | WO | disclosed |