SCHEMBL30953922

SCHEMBL30953922

O=C(Nc1nccc(N2CCC(F)CC2)n1)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27457432 0.92 KIF18A (0.80) KIF18A
SCHEMBL30953931 0.92 KIF18A (0.76) KIF18A
SCHEMBL27455548 0.92 KIF18A (0.76) KIF18A
SCHEMBL27455552 0.91 KIF18A (0.69) KIF18A
SCHEMBL30953956 0.91 KIF18A (0.69) KIF18A
SCHEMBL27455493 0.90 KIF18A (0.76) KIF18A
SCHEMBL30953946 0.89 KIF18A (0.68) KIF18A
SCHEMBL30953950 0.87 KIF18A (0.71) KIF18A
SCHEMBL22148257 0.86 KIF18A (1.00) KIF18A
SCHEMBL29367889 0.86 KIF18A (1.00) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO claimed
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
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