SCHEMBL30953953

SCHEMBL30953953

Cc1cc(N2CCC(F)(F)CC2)nc(NC(=O)c2ccc(S(C)(=O)=O)cc2N2CCC3(CC2)CC3)n1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455361 1.00 KIF18A (0.73) KIF18A
SCHEMBL27456253 0.92 KIF18A (0.63) KIF18A
SCHEMBL30954027 0.92 KIF18A (0.63) KIF18A
SCHEMBL27457052 0.89 KIF18A (0.75) KIF18A
SCHEMBL30953926 0.89 KIF18A (0.75) KIF18A
SCHEMBL27455936 0.88 KIF18A (0.76) KIF18A
SCHEMBL30953916 0.88 KIF18A (0.76) KIF18A
SCHEMBL30953943 0.88 KIF18A (0.78) KIF18A
SCHEMBL27456255 0.88 KIF18A (0.78) KIF18A
SCHEMBL30953952 0.88 KIF18A (0.65) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO claimed
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
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