SCHEMBL30953959

SCHEMBL30953959

Cc1cc(N2CCC(F)(F)CC2)nc(NC(=O)c2ccc(NS(=O)(=O)CCO)cc2N2CCC(C)(C)CC2)n1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30953924 0.94 KIF18A (0.74) KIF18A
SCHEMBL27455413 0.94 KIF18A (0.84) KIF18A
SCHEMBL30953927 0.92 KIF18A (0.79) KIF18A
SCHEMBL27455593 0.88 KIF18A (0.78) KIF18A
SCHEMBL30953921 0.86 KIF18A (0.76) KIF18A
SCHEMBL29367950 0.86 KIF18A (1.00) KIF18A
SCHEMBL22148437 0.86 KIF18A (1.00) KIF18A
SCHEMBL27455595 0.86 KIF18A (0.77) KIF18A
SCHEMBL27455645 0.85 KIF18A (0.78) KIF18A
SCHEMBL22148564 0.85 KIF18A (1.00) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO claimed
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
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