SCHEMBL30954074

SCHEMBL30954074

COc1c(Cl)cc2c(c1C(=O)O)OCCN2CCCc1ccco1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
DRD3 P35462 3/20 0.35
TSHR P16473 1/20 0.34
PKM P14618 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27434942 1.00 MAPT (0.36) MAPTALDH1A1MEN1KMT2ADRD3
SCHEMBL27434914 0.92 TSHR (0.39) MAPTALDH1A1DRD3TSHRKDM4E
SCHEMBL27435374 0.83 KCNA3 (0.43) ALDH1A1MEN1KMT2ADRD3TSHR
SCHEMBL30954054 0.83 KCNA3 (0.43) ALDH1A1MEN1KMT2ADRD3TSHR
SCHEMBL27435528 0.80 KCNA3 (0.41) ALDH1A1DRD3TSHRKDM4EHSD17B10
SCHEMBL27434671 0.79 TP53 (0.40) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL30954057 0.79 TP53 (0.40) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL27435335 0.79 KDM4E (0.40) ALDH1A1MEN1KMT2ADRD3KDM4E
SCHEMBL30954160 0.79 KDM4E (0.40) ALDH1A1MEN1KMT2ADRD3KDM4E
SCHEMBL30954078 0.79 GRM5 (0.33) ALDH1A1KMT2ADRD3TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP claimed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO claimed
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed