Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 18/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954208 | 1.00 | KHK (0.66) | KHKPDE10AHPGDMAPK1HSD17B10 | |
| SCHEMBL25245072 | 0.93 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL30454944 | 0.93 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL25289832 | 0.93 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL30456470 | 0.84 | KHK (0.62) | KHKPDE10AHPGDMAPK1HSD17B10 | |
| SCHEMBL24699193 | 0.83 | KHK (0.65) | KHKPDE10AHPGD | |
| SCHEMBL30016350 | 0.83 | KHK (0.65) | KHKPDE10AHPGD | |
| SCHEMBL30567304 | 0.81 | KHK (0.67) | KHKPDE10AHPGD | |
| SCHEMBL29030971 | 0.81 | KHK (0.67) | KHKPDE10AHPGD | |
| SCHEMBL29030977 | 0.81 | KHK (0.67) | KHKPDE10AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4434982-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | LG Chem, Ltd. (KR) | 2024-09-25 | — | — | EP | disclosed |
| CN-118414332-A | (S) -2- (2-methylazetidin-1-yl) pyrimidine derivatives and pharmaceutical compositions containing the same | 株式会社LG化学 | 2024-07-30 | — | — | CN | disclosed |