Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954250 | 0.89 | GAA (0.45) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL30954237 | 0.84 | GAA (0.47) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL21178405 | 0.80 | GAA (0.42) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL30799332 | 0.79 | GAA (0.52) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL21284828 | 0.75 | GAA (0.45) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL31730377 | 0.74 | GAA (0.44) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL21178544 | 0.74 | GAA (0.44) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL31704461 | 0.74 | GAA (0.44) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL31704678 | 0.74 | GAA (0.44) | GAAEPHX2KMT2AL3MBTL1KDM1A | |
| SCHEMBL21179064 | 0.74 | GAA (0.44) | GAAEPHX2KMT2AL3MBTL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4624473-A1 | PYRROLO[3,2-D]PYRIMIDIN-4-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co., Ltd. (CN) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024120457-A1 | PYRROLO[3,2-D]PYRIMIDIN-4-ONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2024-06-13 | — | — | WO | disclosed |