Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311466 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL30954510 | 0.84 | ABCB1 (0.38) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL27311600 | 0.84 | ABCB1 (0.38) | KDM4EALDH1A1HPGDGAAHTT | |
| SCHEMBL30954492 | 0.81 | SYK (0.35) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL30954491 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1HPGDHTTHSD17B10 | |
| SCHEMBL23092436 | 0.76 | NOD2 (0.41) | ALDH1A1GAAMEN1KMT2ANPC1 | |
| SCHEMBL29900682 | 0.76 | NOD2 (0.41) | ALDH1A1GAAMEN1KMT2ANPC1 | |
| SCHEMBL2971266 | 0.76 | SRD5A2 (0.47) | MEN1KMT2A | |
| SCHEMBL2984740 | 0.76 | SRD5A2 (0.47) | MEN1KMT2A | |
| SCHEMBL2971271 | 0.76 | SRD5A2 (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |