SCHEMBL30954635

SCHEMBL30954635

Cc1cc(CNC(=O)OC(C)(C)C)ccc1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT5 O14744 1/20 0.48
WDR77 Q9BQA1 1/20 0.48
AAK1 Q2M2I8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NAMPT P43490 2/20 0.39
GAA P10253 1/20 0.38
KDM4A O75164 1/20 0.38
HDAC1 Q13547 1/20 0.38
GRM2 Q14416 1/20 0.38
GLS O94925 1/20 0.37
BRD4 O60885 2/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
CREBBP Q92793 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20095411 0.87 PRMT5 (0.48) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL29924642 0.87 PRMT5 (0.48) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL29925213 0.87 PRMT5 (0.48) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL24619251 0.87 PRMT5 (0.48) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL24619217 0.84 PRMT5 (0.46) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL31694714 0.84 PRMT5 (0.46) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL30954637 0.84 PRMT5 (0.45) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL24619901 0.84 PRMT5 (0.45) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL29924784 0.84 PRMT5 (0.45) PRMT5WDR77AAK1L3MBTL1NAMPT
SCHEMBL22409228 0.83 PRMT5 (0.44) PRMT5WDR77AAK1L3MBTL1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4628488-A1 CYCLIN K DEGRADER AND USE THEREOF Adlai Nortye Biopharma Co., Ltd. (CN) 2025-10-08 EP disclosed