Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954635 | 0.84 | PRMT5 (0.48) | PRMT5WDR77AAK1L3MBTL1GLS | |
| SCHEMBL20095411 | 0.83 | PRMT5 (0.48) | PRMT5WDR77AAK1L3MBTL1GLS | |
| SCHEMBL29924642 | 0.83 | PRMT5 (0.48) | PRMT5WDR77AAK1L3MBTL1NAMPT | |
| SCHEMBL29925213 | 0.83 | PRMT5 (0.48) | PRMT5WDR77AAK1L3MBTL1GLS | |
| SCHEMBL24619251 | 0.83 | PRMT5 (0.48) | PRMT5WDR77AAK1L3MBTL1NAMPT | |
| SCHEMBL29780075 | 0.82 | SIRT2 (0.42) | AAK1CA1MAPTCA9LMNA | |
| SCHEMBL28680365 | 0.82 | SIRT2 (0.42) | AAK1CA1MAPTCA9LMNA | |
| SCHEMBL30877934 | 0.81 | AAK1 (0.38) | PRMT5WDR77AAK1CA1CA2 | |
| SCHEMBL31694714 | 0.80 | PRMT5 (0.46) | PRMT5WDR77AAK1L3MBTL1GLS | |
| SCHEMBL24619217 | 0.80 | PRMT5 (0.46) | PRMT5WDR77AAK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4628488-A1 | CYCLIN K DEGRADER AND USE THEREOF | Adlai Nortye Biopharma Co., Ltd. (CN) | 2025-10-08 | — | — | EP | disclosed |