Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 13/20 | 0.42 |
| ▸ | NCF1 | P14598 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265296 | 0.90 | MAPT (0.43) | MAPTMAPK1TDP1MEN1NPC1 | |
| SCHEMBL30954748 | 0.85 | MAPT (0.50) | MAPTAPPNCF1 | |
| SCHEMBL23412255 | 0.78 | KDM4E (0.62) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL23412131 | 0.78 | KDM4E (0.62) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL23412356 | 0.78 | KDM4E (0.62) | MAPTMAPK1TDP1NPC1RAB9A | |
| SCHEMBL3284522 | 0.77 | MAPT (0.61) | MAPTMAPK1TDP1MEN1NPC1 | |
| SCHEMBL30954751 | 0.76 | MAPT (0.47) | MAPTTDP1APPKDM4E | |
| SCHEMBL30954750 | 0.74 | APP (0.46) | MAPTMAPK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23412840 | 0.73 | TDP1 (0.60) | MAPTMAPK1TDP1MEN1NPC1 | |
| SCHEMBL30954752 | 0.73 | MAPT (0.49) | MAPTL3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290352-A | Azo compound, preparation method and application thereof, and medicinal composition | 四川大学 | 2024-07-05 | — | — | CN | disclosed |