Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954691 | 0.81 | BACE1 (0.50) | BACE1MAPTLMNA | |
| SCHEMBL30954693 | 0.81 | BACE1 (0.50) | BACE1MAPTLMNA | |
| SCHEMBL8402825 | 0.79 | CA9 (0.38) | BACE1MAPTGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6927966 | 0.78 | HTR1D (0.39) | MAPTKDM4EPRSS1PRSS2PRSS3 | |
| SCHEMBL6603179 | 0.78 | CYP2D6 (0.39) | PRSS1PRSS2PRSS3 | |
| SCHEMBL30954739 | 0.76 | TNKS (0.39) | — | |
| SCHEMBL30974103 | 0.74 | AKR1B1 (0.45) | BACE1MAPT | |
| SCHEMBL8353721 | 0.74 | HTR1D (0.37) | MAPTGAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6603189 | 0.73 | S1PR5 (0.39) | PRSS1PRSS2PRSS3 | |
| SCHEMBL15542586 | 0.71 | MAPT (0.44) | BACE1MAPTGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125488-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2024-06-20 | — | — | WO | disclosed |