Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3742950 | 0.88 | HTR2C (0.46) | AKR1B1AKR1B10MAPTAKR1A1CHRNA7 | |
| Hydrochloric Acid SCHEMBL2800247 | 0.87 | HTR2C (0.44) | AKR1B1AKR1B10MAPTAKR1A1CHRNA7 | |
| SCHEMBL8062832 | 0.85 | AKR1B1 (0.48) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL30353231 | 0.83 | AKR1B1 (0.55) | AKR1B1AKR1B10MAPTAKR1A1KDM1A | |
| SCHEMBL12084199 | 0.79 | OPRM1 (0.41) | AKR1B1CHRNA7 | |
| SCHEMBL30697940 | 0.77 | BACE1 (0.50) | MAPTBACE1 | |
| SCHEMBL16659190 | 0.77 | CYP3A4 (0.44) | MAPT | |
| SCHEMBL13226300 | 0.75 | ALDH1A1 (0.42) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL12899197 | 0.75 | ALDH1A1 (0.42) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL13640842 | 0.75 | CHRNA7 (0.41) | AKR1B1AKR1B10MAPTAKR1A1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118930547-A | Ureido-substituted fused heteroaryl compounds, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118515674-A | Amide compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-20 | — | — | CN | disclosed |