SCHEMBL30954965

SCHEMBL30954965

Cc1cn(-c2c(F)cc(N)cc2F)c(Br)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15062278 0.83 NR3C1 (0.34)
SCHEMBL30954923 0.79 PLAU (0.34)
SCHEMBL30954983 0.77 S1PR4 (0.36)
SCHEMBL3325025 0.69 TAAR1 (0.33)
SCHEMBL962723 0.66 GRM5 (0.42)
SCHEMBL2254115 0.66 NR2E1 (0.53)
SCHEMBL16339165 0.63 TLR9 (0.41)
Hydrochloric Acid SCHEMBL16339034 0.62 TLR9 (0.41)
Hydrochloric Acid SCHEMBL29256940 0.62 TLR9 (0.41)
SCHEMBL27217202 0.62 HSD17B10 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626546-A1 HETEROCYCLIC COMPOUND AND USE THEREOF Takeda Pharmaceutical Company Limited (JP) 2025-10-08 EP disclosed
WO-2024116086-A1 HETEROCYCLIC COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-06-06 WO disclosed