Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.54 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.32 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955598 | 0.95 | ERN1 (0.47) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955493 | 0.91 | ERN1 (0.54) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955566 | 0.88 | ERN1 (0.60) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955607 | 0.87 | ERN1 (0.59) | ERN1TNK2MAP4K2FGFR4EGFR | |
| SCHEMBL30955617 | 0.87 | ERN1 (0.41) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955542 | 0.87 | ERN1 (0.49) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955483 | 0.87 | ERN1 (0.54) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955530 | 0.85 | ERN1 (0.47) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955613 | 0.85 | ERN1 (0.47) | ERN1TNK2MAP4K2FGFR4MAPK1 | |
| SCHEMBL30955606 | 0.85 | ERN1 (0.47) | ERN1FGFR4MAPK1EGFRFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | claimed |
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |