Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.59 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | JAK2 | O60674 | 5/20 | 0.33 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955566 | 0.93 | ERN1 (0.60) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955483 | 0.89 | ERN1 (0.54) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955493 | 0.89 | ERN1 (0.54) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955563 | 0.87 | ERN1 (0.54) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955542 | 0.85 | ERN1 (0.49) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955530 | 0.83 | ERN1 (0.47) | ERN1TNK2MAP4K2EGFRCDK2 | |
| SCHEMBL30955613 | 0.83 | ERN1 (0.47) | ERN1TNK2MAP4K2CSF1REGFR | |
| SCHEMBL30955606 | 0.82 | ERN1 (0.47) | ERN1CSF1REGFRBRD4FGFR1 | |
| SCHEMBL30955678 | 0.82 | ERN1 (0.38) | ERN1BRD4BRD2BRD3BRDT | |
| SCHEMBL30955633 | 0.81 | ERN1 (0.39) | ERN1BRD4CCNA2CDK2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | claimed |
| WO-2024131893-A1 | IRE1α SMALL MOLECULE INHIBITORS | SHANGHAI YI ZHONG XING BIOTECHNOLOGY CO., LTD. (CN) | 2024-06-27 | — | — | WO | disclosed |